Article

Mechanisms Underlying WNT-mediated Priming of Human Embryonic Stem Cells

2021-05-01

Abstract excerpt

Embryogenesis is guided by a limited set of signaling pathways dynamically expressed in different places. How a context dependent signaling response is generated has been a central question of developmental biology, which can now be addressed with in vitro models of human embryos that are derived from embryonic stem cells (hESCs) called gastruloids. Our previous work demonstrated that during early self-organizati...

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Literature Corpus work: 67a229ea-ea82-59c3-8109-08d54423ef8b
DOI: 10.1101/2021.05.01.442278

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