Article

A novel self-organizing embryonic stem cell system reveals signaling logic underlying the patterning of human ectoderm

2019-01-11

Abstract excerpt

<h4>Summary</h4> During development, the ectoderm is patterned by a combination of BMP and WNT signaling. Research in model organisms has provided substantial insight, however, there are currently no systems to study this patterning in humans. Further, the complexity of neural plate border specification has made it difficult to transition from discovering the genes involved to deeper mechanistic understanding. He...

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Literature Corpus work: 5f69581c-1c30-5686-8ad8-814ec0fefeca
DOI: 10.1101/518803

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