Article

Epigenetic priming of embryonic enhancer elements coordinates developmental gene networks

2024-09-10

Abstract excerpt

Embryonic development requires the accurate spatiotemporal execution of cell lineage-specific gene expression programs, which are controlled by transcriptional enhancers. Developmental enhancers adopt a primed chromatin state prior to their activation; however how this primed enhancer state is established, maintained, and how it affects the regulation of developmental gene networks remains poorly understood. Here,...

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Literature Corpus work: 5e372af8-683f-54fc-9ee1-af378a6d07a7
DOI: 10.1101/2024.09.09.611867

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