Article

Trans-ethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals shared but also ethnicity-specific disease associations

2020-07-30

Abstract excerpt

<h4>ABSTRACT</h4> Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gut. Genetic association studies have identified the highly variable human leukocyte antigen (HLA) region as the strongest susceptibility locus for IBD, and specifically DRB1*01:03 as a determining factor for ulcerative colitis (UC). However, for most of the association signal such a delineation could not be made due to tig...

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Literature Corpus work: 653132e3-d722-5983-bf72-198790569200
DOI: 10.1101/2020.07.29.20162552

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