Article
Inflammatory bowel disease: susceptibility and disease heterogeneity revealed by human leukocyte antigen genotyping.
Genetic testing and molecular biomarkers - 1 Jun 2012
Bouzid Dorra, Kammoun Arwa, Amouri Ali, Mahfoudh Nadia, Haddouk Samy, Tahri Nabil, Makni Hafedh, Masmoudi Hatem
Abstract excerpt
This study aimed to investigate the association between HLA DR/DQ and inflammatory bowel diseases (IBD) in Tunisian patients and to determine the relationship between HLA DR/DQ alleles with the clinical disease patterns. DNA typing of human leukocyte antigen (HLA) genes was performed in 70 ulcerative colitis (UC) patients, 40 Crohn's disease (CD) patients, and 123 healthy controls (HC) using a polymerase chain...
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