Article

The fat gene cooperates with the Hippo pathway to prevent neuronal degeneration

2010-01-01

Abstract excerpt

Fat is a cadherin that regulates planar polarity and acts as a tumor suppressor both in vertebrates and invertebrates. <i>Drosophila fat</i> recessive mutations have been shown to induce an excessive cell proliferation and a hyperplastic tissue overgrowth during larval development. Fat has recently been described to be part of a signaling cascade, the Hippo tumor suppressor pathway, which regulates organ size and...

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Literature Corpus work: 64adf257-410d-595b-b617-04aa2133011a
DOI: 10.21954/ou.ro.0000f1f9

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