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Article

The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.

Current biology : CB - 7 Nov 2006

Willecke Maria, Hamaratoglu Fisun, Kango-Singh Madhuri, Udan Ryan, Chen Chiao-Lin, Tao Chunyao, Zhang Xinwei, Halder Georg

Abstract excerpt

BACKGROUND: The Hippo tumor-suppressor pathway has emerged as a key signaling pathway that controls tissue size in Drosophila. Merlin, the Drosophila homolog of the human Neurofibromatosis type-2 (NF2) tumor-suppressor gene, and the related protein Expanded are the most upstream components of the Hippo pathway identified so far. However, components acting upstream of Expanded and Merlin, such as transmembrane...

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Identifiers

PMID: 16996265
DOI: 10.1016/j.cub.2006.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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