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Article

Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor

2020-07-25

Abstract excerpt

<h4>ABSTRACT</h4> The degeneration of dopaminergic (DA) neurons in the substantia nigra is a hallmark of Parkinson’s disease (PD). Dysregulation of developmental transcription factors is implicated in dopaminergic neurodegeneration, but the underlying molecular mechanisms remain largely unknown. Drosophila Fer2 is a prime example of a developmental transcription factor required for the birth and maintenance of m...

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Literature Corpus work
2d74fe68-26ba-5bec-98fd-862d9d1b5164
DOI
10.1101/2020.07.24.219246
Open publication

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Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factorDOI 10.1101/2020.07.24.219246
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