Article

LINE-1 Retrotransposon expression in cancerous, epithelial and neuronal cells revealed by 5’ single-cell RNA-Seq

2021-01-20

Abstract excerpt

LINE-1 retrotransposons are sequences capable of copying themselves to new genomic loci via an RNA intermediate. New studies implicate LINE-1 in a range of diseases, especially in the context of aging, but without an accurate understanding of where and when LINE-1 is expressed, a full accounting of its role in health and disease is not possible. We therefore developed a method – 5’ scL1seq – that makes use of a wi...

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Literature Corpus work: 64acd05c-8115-5743-aff9-489b6be2802b
DOI: 10.1101/2021.01.19.427347

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