Article

L1EM: A tool for accurate locus specific LINE-1 RNA quantification

2019-07-24

Abstract excerpt

<h4>Motivation</h4> LINE-1 elements are retrotransposons that are capable of copying their sequence to new genomic loci. LINE-1 derepression is associated with a number of disease states, and has the potential to cause significant cellular damage. Because LINE-1 elements are repetitive, it is difficult to quantify RNA at specific LINE-1 loci and to separate transcripts with protein coding capability from other so...

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Literature Corpus work: 63452808-92d9-5067-83e2-112ba344012f
DOI: 10.1101/714014

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