Article

TeXP: Deconvolving the effects of pervasive and autonomous transcription of transposable elements

2019-05-24

Abstract excerpt

Long interspersed nuclear element 1 (LINE-1) is a primary source of genetic variation in humans and other mammals. Despite its importance, LINE-1 activity remains difficult to study because of its highly repetitive nature. Here, we developed and validated a method called TeXP to gauge LINE-1 activity accurately. TeXP builds mappability signatures from LINE-1 subfamilies to deconvolve the effect of pervasive transc...

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Literature Corpus work: 49d4a6c3-9083-5685-9303-d610153f3cac
DOI: 10.1101/648667

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