Article

Combining in silico and experimental methods to dissect the impact of L1 retrotransposons on the human transcriptome

2019-01-01

Abstract excerpt

Only the L1 family of LINEs is still active in humans, continuing to sculpt our genome by their mobilization. Databases documenting L1 diversity indicate that approximately 90% of the youngest human specific (L1Hs) show polymorphisms between individuals and many insertions occur within annotated genes. Retrotransposon Insertion Polymorphisms (RIPs), similar to other human genomic variation, such as copy number var...

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Literature Corpus work: 32569378-9f63-5915-9aa8-c79031fc8fb0
DOI: 10.25392/leicester.data.10303838.v1

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