Article

Predicting clone genotypes from tumor bulk sequencing of multiple samples

2018-06-07

Abstract excerpt

<h4>Motivation</h4> Analyses of data generated from bulk sequencing of tumors have revealed extensive genomic heterogeneity within patients. Many computational methods have been developed to enable the inference of genotypes of tumor cell populations (clones) from bulk sequencing data. However, the relative and absolute accuracy of available computational methods in estimating clone counts and clone genotypes is...

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Literature Corpus work: 63d1cfef-2cf5-5d2e-b922-54f15825db9b
DOI: 10.1101/341180

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