Article

Estimation of cancer cell fractions and clone trees from multi-region sequencing of tumors

2021-06-13

Abstract excerpt

<h4> A bstract </h4> Multi-region sequencing of one or multiple biopsies of solid tumors from a patient can be used to improve our understanding of the diversity of subclones in the patient’s tumor and shed light on the evolutionary history of the disease. Due to the large number of possible evolutionary relationships between clones and the fundamental uncertainty of the mutational composition of subclones, elu...

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Literature Corpus work: de9c3792-01d5-5454-bedc-63ef28d201be
DOI: 10.1101/2021.06.12.448194

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