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Article

Predicting clone genotypes from tumor bulk sequencing of multiple samples.

Bioinformatics (Oxford, England) - 1 Dec 2018

Miura Sayaka, Gomez Karen, Murillo Oscar, Huuki Louise A, Vu Tracy, Buturla Tiffany, Kumar Sudhir

Abstract excerpt

Motivation: Analyses of data generated from bulk sequencing of tumors have revealed extensive genomic heterogeneity within patients. Many computational methods have been developed to enable the inference of genotypes of tumor cell populations (clones) from bulk sequencing data. However, the relative and absolute accuracy of available computational methods in estimating clone counts and clone genotypes is not yet...

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Identifiers

PMID: 29931046
DOI: 10.1093/bioinformatics/bty469
PMCID: PMC6247940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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