Article

Co-regulatory changes in <i>Homo sapiens</i> prefrontal cortex shape RNA-chromatin interactions

2026-03-17

Abstract excerpt

Noncoding RNAs (ncRNAs) regulate gene expression through RNA–chromatin interactions, yet their role in human brain evolution remains unclear. To map these interactions, we integrated FANTOM6 neurogenic data with a comprehensive atlas of regulatory regions active during early cortical development. This integration effort linked ncRNAs and transcription factors (TFs) to their genomic targets, revealing functional in...

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Literature Corpus work: 62eea379-781b-5bb4-bfd8-cfbce534a068
DOI: 10.64898/2026.03.14.711601

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