Article

Interrogating the Regulatory Function of HAQERs during Human Cortical Development

2025-12-01

Abstract excerpt

<h4>Background</h4> Sequence divergence within gene regulatory elements has been proposed to play an important role in the evolution of human-specific traits, including cortical expansion. However, the mutational processes that efficiently modify gene regulatory elements and the target genes upon which they act are poorly understood. We investigated the regulatory function and origins of the fastest evolved regio...

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Literature Corpus work: b04da07c-2267-5f63-8661-2bc056ac0ed8
DOI: 10.1101/2025.11.30.691411

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