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Article

Modern human changes in regulatory regions implicated in cortical development.

BMC genomics - 16 Apr 2020

Moriano Juan, Boeckx Cedric

Abstract excerpt

BACKGROUND: Recent paleogenomic studies have highlighted a very small set of proteins carrying modern human-specific missense changes in comparison to our closest extinct relatives. Despite being frequently alluded to as highly relevant, species-specific differences in regulatory regions remain understudied. Here, we integrate data from paleogenomics, chromatin modification and physical interaction, and...

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Identifiers

PMID: 32299352
DOI: 10.1186/s12864-020-6706-x
PMCID: PMC7161147

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