Article

Hominin-specific NOTCH2 paralogs expand human cortical neurogenesis through regulation of Delta/Notch interactions

2017-11-17

Abstract excerpt

<h4>Summary</h4> The human cerebral cortex has undergone rapid expansion and increased complexity during recent evolution. Hominid-specific gene duplications represent a major driving force of evolution, but their impact on human brain evolution remains unclear. Using tailored RNA sequencing (RNAseq), we profiled the spatial and temporal expression of Hominid-specific duplicated (HS) genes in the human fetal cort...

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Literature Corpus work: 4f184d21-1421-5d8a-b142-a32c2ecc1529
DOI: 10.1101/221358

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