Article

Robust expression of LINE-1 retrotransposon encoded proteins in oral squamous cell carcinoma

2020-11-24

Abstract excerpt

Retrotransposons are sequences which transpose within genomes using RNA as an intermediate. Long INterpersed Element-1 (LINE1 or L1) is the only active retrotransposon occupying around 17% of the human genome with an estimated 500,000 copies. An active L1 encodes two proteins (L1ORF1p and L1ORF2p); both of which are critical in the process of retrotransposition. In-order to propagate to the nextgeneration, L1s rem...

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Literature Corpus work: 62e59701-0df7-58ee-92ca-2599c45e99fa
DOI: 10.1101/2020.11.24.395285

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