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RetroTest unravels LINE-1 retrotransposition in Head and Neck Squamous Cell Carcinoma

2024-07-24

Abstract excerpt

The relevant role of LINE-1 (L1) retrotransposition in cancer has been recurrently demonstrated in recent years. However, their repetitive nature hampers their identification and detection, hence remaining inaccessible for clinical practice. Also, its clinical relevance for cancer patients is still limited. Here, we develop a new method to quantify L1 activation, called RetroTest, based on targeted sequencing and...

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Identifiers and source

Literature Corpus work
c53a910e-fbe8-5494-b1ef-a34650d6fb84
DOI
10.1101/2024.07.24.24310921
Open publication

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RetroTest unravels LINE-1 retrotransposition in Head and Neck Squamous Cell CarcinomaDOI 10.1101/2024.07.24.24310921
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