Article

Myeloid Cell Derived IL1β Contributes to Pulmonary Vascular Remodeling in Heart Failure with Preserved Ejection Fraction

2023-05-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Pulmonary hypertension (PH) in heart failure with preserved ejection fraction (HFpEF) is a common and highly morbid syndrome, but mechanisms driving PH-HFpEF are not well understood. We sought to determine whether a well-accepted murine model of HFpEF also displays features of PH in HFpEF, and we sought to identify pathways that might drive early remodeling of the pulmonary...

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Literature Corpus work: 61d81797-5d03-5b57-8fc5-777175280551
DOI: 10.1101/2023.05.18.541302

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