Article

Bone marrow mesenchymal stromal cells mediate cellular inflammation in HFpEF

2025-04-02

Abstract excerpt

<h4>Summary</h4> During the genesis of heart failure, the myocardium recruits an abundance of bone marrow-derived leukocytes, primarily monocytes, with various disease-promoting functions. Increased hematopoiesis fuels these unfavorable changes in cardiac leukocyte origin, number and phenotype. Here we examine hematopoietic niche cells, which regulate blood progenitor proliferation and systemic monocyte supply, i...

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Literature Corpus work: 8361f799-94c6-507f-89bd-578ed45bbd31
DOI: 10.1101/2025.03.28.645924

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