Article
RNA Sequencing Screens the Key Genes and Pathways in a Mouse Model of HFpEF.
Journal of vascular research - 1 Jan 2024
Sun Yuxi, Li Jiaxin, Zhang Xinxin, Wang Ning, Liu Ying
Abstract excerpt
INTRODUCTION: Heart failure with preserved ejection fraction (HFpEF) is a common syndrome with high morbidity and mortality but without available evidence-based therapies. It is essential to investigate changes in gene expression profiles in preclinical HFpEF animal models, with the aim of searching for novel therapeutic targets. METHODS: Wild-type male C57BL/6J mice were administrated with a combination of...
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