Article

Free fatty acid receptor 4 is a nutrient sensor that resolves inflammation to maintain cardiac homeostasis

2019-09-19

Abstract excerpt

<h4>Background</h4> Non-resolving activation of immune responses is central to the pathogenesis of heart failure (HF). Free fatty acid receptor 4 (Ffar4) is a G-protein coupled receptor (GPR) for medium-and long-chain fatty acids (FA) that regulates metabolism and attenuates inflammation in diabetes and obesity. Here, we tested the hypothesis that Ffar4 functions as a cardioprotective nutrient sensor that resolv...

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Literature Corpus work: 2c0e3cb5-3f48-57d8-bd4e-28032547895b
DOI: 10.1101/776294

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