Article

Precise, pan-cancer discovery of gene fusions reveals a signature of selection in primary tumors

2017-08-18

Abstract excerpt

<h4>Short Abstract</h4> The extent to which gene fusions function as drivers of cancer remains a critical open question in cancer biology. In principle, transcriptome sequencing provided by The Cancer Genome Atlas (TCGA) enables unbiased discovery of gene fusions and post-analysis that informs the answer to this question. To date, such an analysis has been impossible because of performance limitations in fusion d...

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Literature Corpus work: 610ced2c-9d2a-5723-a99b-ec7e9aeea122
DOI: 10.1101/178061

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