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ImmunoFusion: A Unified Platform for Investigating RNA-seq-Derived Gene Fusions in Cancer and Immunotherapy

2025-06-08

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Gene fusions play a critical role in cancer development by persistently activating kinases or inactivating tumor suppressor genes, leading to altered signal transduction and gene expression regulation. However, their impact on treatment responses remains poorly understood. Although existing cancer databases catalog numerous fusion events or immune checkpoint blockade (ICB) s...

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Literature Corpus work
16e9efea-6060-53b9-8cd9-d467ddf47541
DOI
10.1101/2025.06.05.658082
Open publication

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ImmunoFusion: A Unified Platform for Investigating RNA-seq-Derived Gene Fusions in Cancer and ImmunotherapyDOI 10.1101/2025.06.05.658082
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