Article
TumorFusions: an integrative resource for cancer-associated transcript fusions.
Nucleic acids research - 4 Jan 2018
Hu Xin, Wang Qianghu, Tang Ming, Barthel Floris, Amin Samirkumar, Yoshihara Kosuke, Lang Frederick M, Martinez-Ledesma Emmanuel, Lee Soo Hyun, Zheng Siyuan, Verhaak Roel G W
Abstract excerpt
Gene fusion represents a class of molecular aberrations in cancer and has been exploited for therapeutic purposes. In this paper we describe TumorFusions, a data portal that catalogues 20 731 gene fusions detected in 9966 well characterized cancer samples and 648 normal specimens from The Cancer Genome Atlas (TCGA). The portal spans 33 cancer types in TCGA. Fusion transcripts were identified via a uniform...
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