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Article

Fusion genes: A promising tool combating against cancer.

Biochimica et biophysica acta. Reviews on cancer - 1 Apr 2018

Dai Xiaofeng, Theobard Rutaganda, Cheng Hongye, Xing Mengtao, Zhang Jianying

Abstract excerpt

The driving roles of fusion genes during tumorigenesis have been recognized for decades, with efficacies demonstrated in clinical diagnosis and targeted therapy. With advances in sequencing technologies and computational biology, a surge in the identification of fusion genes has been witnessed during the past decade. The discovery and presence of splicing based fusions in normal tissues have challenged our...

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PMID: 29357299
DOI: 10.1016/j.bbcan.2017.12.003

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