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Article

Fusion genes and their discovery using high throughput sequencing.

Cancer letters - 1 Nov 2013

Annala M J, Parker B C, Zhang W, Nykter M

Abstract excerpt

Fusion genes are hybrid genes that combine parts of two or more original genes. They can form as a result of chromosomal rearrangements or abnormal transcription, and have been shown to act as drivers of malignant transformation and progression in many human cancers. The biological significance of fusion genes together with their specificity to cancer cells has made them into excellent targets for molecular...

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Identifiers

PMID: 23376639
DOI: 10.1016/j.canlet.2013.01.011
PMCID: PMC3675181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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