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LTD-inducing low frequency stimulation enhances p-Tau181 and p-Tau217 in an age-dependent manner in live rats

2022-03-29

Abstract excerpt

The progressive cognitive decline in Alzheimer’s disease (AD) patients correlates with the extent of tau pathology, in particular tau hyperphosphorylation, which is strongly age-associated. Although elevation of phosphorylated tau (p-Tau) on residues Thr181 (p-Tau181), Thr217 (p-Tau217), and Thr231 (p-Tau231) in cerebrospinal fluid or blood are recently proposed to be particularly sensitive markers of early AD, th...

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Literature Corpus work
5fceadf1-4d05-53f0-bec8-b7580ce811ae
DOI
10.1101/2022.03.28.486022
Open publication

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LTD-inducing low frequency stimulation enhances p-Tau181 and p-Tau217 in an age-dependent manner in live ratsDOI 10.1101/2022.03.28.486022
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