Article

Aη-α and Aη-β peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo.

2021-03-10

Abstract excerpt

<title>Abstract</title> <p>Background Amyloid precursor protein (APP) processing is central to Alzheimer’s disease (AD) etiology. As early cognitive alterations in AD are strongly correlated to abnormal information processing due to increasing synaptic impairment, it is crucial to characterize how peptides generated through APP cleavage modulate synapse function. We previously described a novel APP processing pa...

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Literature Corpus work: eee35c9a-ffb7-59bc-a83b-e626e822121c
DOI: 10.21203/rs.3.rs-259533/v1

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Aη-α and Aη-β peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo.DOI 10.21203/rs.3.rs-259533/v1Read

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