Article

ENT1 inhibition rescues energy dysfunction and pathology in a model of tauopathy

2024-01-30

Abstract excerpt

<h4>Background: </h4> and Purpose: Tau pathology is instrumental in the gradual loss of neuronal functions and cognitive decline in tauopathies, including Alzheimer’s disease (AD). Adenosine homeostasis is essential to brain metabolism and plasticity but the link to Tau remained ill-defined. Herein, we aimed at investigating whether modulating adenosine tone, through pharmacological manipulation of equilibrative n...

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Literature Corpus work: a9e13e8c-571e-504c-8574-b645cab6f4be
DOI: 10.22541/au.170665248.82087440/v1

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