Article

Strategic Modulation of Polarity and Viscosity Sensitivity of Bimane Molecular Rotor-Based Fluorophores for Imaging α-Synuclein

2025-01-09

Abstract excerpt

<h4>ABSTRACT</h4> Molecular rotor-based fluorophores (RBFs) that are target-selective and sensitive to both polarity and viscosity are valuable for diverse biological applications. Here, we have designed next-generation RBFs based on the underexplored bimane fluorophore through either changing in aryl substitution or varying π-linkages between the rotatable electron donors and acceptors to produce red-shifted flu...

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Literature Corpus work: 5eec7d25-5922-5d4c-835a-a380d035e49d
DOI: 10.1101/2025.01.07.631748

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