Article

Sequencing of <i>α</i> -synuclein Intrinsically Disordered Protein in MoS <sub>2</sub> Nanopores

2025-07-26

Abstract excerpt

<h4>ABSTRACT</h4> α -synuclein is an intrinsically disordered protein composed of 140 amino acids that adopts multiple conformations and is prone to aggregate into β -sheet-rich structures, which are hallmarks of Parkinson’s disease. Moreover, missense mutations in α -synuclein are related to familial forms of this neurodegenerative disorder, making their detection at the single-molecule level essential. Recent...

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Literature Corpus work: 59cfb555-9082-5b45-80e1-09a7fcb23d06
DOI: 10.1101/2025.07.23.666249

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