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Article

Chromatin Landscape of Cancer Cell Lines Identifies Enhancer Subtypes

2026-08-04

Abstract excerpt

<h4>ABSTRACT</h4> Epigenetic aberrations are a hallmark of cancer; however, systematic chromatin state maps of cancer cells are unavailable. We generated and analyzed 803 histone mark profiles in 142 cancer cell lines and 114 human tumors belonging to 9 solid tumor types. Irrespective of their cell-of-origin, cancer cells segregate from normal tissues based on their enhancer patterns, suggesting enhancer deregula...

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Literature Corpus work
5e46c25e-9eb1-5752-8d82-40933d7172cb
DOI
10.64898/2026.08.01.741526
Open publication

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Chromatin Landscape of Cancer Cell Lines Identifies Enhancer SubtypesDOI 10.64898/2026.08.01.741526
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