Article

Integrative Epigenomic and High-Throughput Functional Enhancer Profiling Reveals Determinants of Enhancer Heterogeneity in Gastric Cancer

2021-06-10

Abstract excerpt

<h4>Background</h4> Enhancers are distal cis -regulatory elements required for cell-specific gene expression and cell fate determination. In cancer, enhancer variation has been proposed as a major cause of inter-patient heterogeneity – however, most predicted enhancer regions remain to be functionally tested. <h4>Results</h4> Analyzing 128 epigenomic histone modification profiles of primary GC samples, normal...

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Literature Corpus work: a5be0349-f233-5935-bc43-d63ee0e97377
DOI: 10.1101/2021.06.09.447637

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