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Article

Age, nutritional status and INH acetylator status affect pharmacokinetics of anti-tuberculosis drugs in children.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Jun 2013

Ramachandran G, Hemanth Kumar A K, Bhavani P K, Poorana Gangadevi N, Sekar L, Vijayasekaran D, Banu Rekha V V, Ramesh Kumar S, Ravichandran N, Mathevan G, Swaminathan S

Abstract excerpt

SETTING: The currently recommended dosages of rifampicin (RMP), isoniazid (INH), pyrazinamide (PZA) and ethambutol in children are extrapolated from adult pharmacokinetic studies, and have not been adequately evaluated in children. OBJECTIVE: To describe the pharmacokinetics of RMP, INH and PZA given thrice weekly in children with tuberculosis (TB), and to relate pharmacokinetics to treatment outcomes. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23676165
DOI: 10.5588/ijtld.12.0628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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