Article

Molecular and genetic heterogeneity in iPSCs derived from an outbred laboratory mouse population

2026-05-03

Abstract excerpt

<h4>ABSTRACT</h4> Genetically diverse panels of human pluripotent stem cells enable genetic dissection of cellular phenotypes, but comparable induced pluripotent stem cell (iPSC) resources in model organisms remain limited. We generated a panel of iPSCs from the Diversity Outbred (DO) mouse population and established 288 genetically unique lines that retain the allele frequency distribution, heterozygosity, and l...

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Literature Corpus work: 5cbd94b4-4b1d-5a6e-8708-f53f671e2691
DOI: 10.64898/2026.05.02.722403

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