Article

Genetic dissection of the pluripotent proteome through multi-omics data integration

2022-04-22

Abstract excerpt

Genetic background is a major driver of phenotypic variability in pluripotent stem cells (PSCs). Most studies of variation in PSCs have relied on transcript abundance as the primary molecular readout of cell state. However, little is known about how proteins, the primary functional units in the cell, vary across genetically diverse PSCs, how protein abundance relates to variation in other cell characteristics, and...

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Literature Corpus work: 2c892914-3494-5089-89be-12be02f8713f
DOI: 10.1101/2022.04.22.489216

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