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Article

Common genetic variation drives molecular heterogeneity in human IPSCs

2016-05-25

Abstract excerpt

Induced pluripotent stem cell (iPSC) technology has enormous potential to provide improved cellular models of human disease. However, variable genetic and phenotypic characterisation of many existing iPSC lines limits their potential use for research and therapy. Here, we describe the systematic generation, genotyping and phenotyping of 522 open access human iPSCs derived from 189 healthy male and female individua...

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Identifiers and source

Literature Corpus work
ae596223-5cdf-5b23-9627-430896702700
DOI
10.1101/055160
Open publication

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Common genetic variation drives molecular heterogeneity in human IPSCsDOI 10.1101/055160
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