Article

A Pluripotent Stem Cell Platform for in Vitro Systems Genetics Studies of Mouse Development

2024-06-06

Abstract excerpt

<h4>SUMMARY</h4> The directed differentiation of pluripotent stem cells (PSCs) from panels of genetically diverse individuals is emerging as a powerful experimental system for characterizing the impact of natural genetic variation on developing cell types and tissues. Here, we establish new PSC lines and experimental approaches for modeling embryonic development in a genetically diverse, outbred mouse stock (Dive...

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Literature Corpus work: d6f01074-ec00-52e0-82f0-82fabcff5165
DOI: 10.1101/2024.06.06.597758

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