Article
Mouse Genetic Reference Populations: Cellular Platforms for Integrative Systems Genetics.
Trends in genetics : TIG - 1 Mar 2021
Swanzey Emily, O'Connor Callan, Reinholdt Laura G
Abstract excerpt
Interrogation of disease-relevant cellular and molecular traits exhibited by genetically diverse cell populations enables in vitro systems genetics approaches for uncovering the basic properties of cellular function and identity. Primary cells, stem cells, and organoids derived from genetically diverse mouse strains, such as Collaborative Cross and Diversity Outbred populations, offer the opportunity for parallel...
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