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Low-coverage whole-genome sequencing facilitates accurate and cost-effective haplotype reconstruction in complex mouse crosses

2025-05-19

Abstract excerpt

<h4>ABSTRACT</h4> The search for the underlying genetic contributions to complex traits and diseases relies on accurate genetic data from populations of interest. Outbred populations, like the Diversity Outbred (DO), are commonly genotyped using commercial SNP arrays, such as the Giga Mouse Universal Genotyping Array (GigaMUGA). However, array genotypes are expensive to collect, subject to significant ascertainme...

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Literature Corpus work
708540f5-2c9f-532d-9659-4dc70f8d2c24
DOI
10.1101/2025.05.19.654056
Open publication

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Low-coverage whole-genome sequencing facilitates accurate and cost-effective haplotype reconstruction in complex mouse crossesDOI 10.1101/2025.05.19.654056
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