Article
The role of the Parkinson's disease-related protein LRRK2 in autophagy and calcium signalling in cellular models
2021-01-01
Abstract excerpt
Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide, affecting 3% of individuals of >75 years of age. The disease is relentless and incurable, and the need to understand its causes and develop new treatments is overwhelming. Mutations in the LRRK2 gene are the most common cause of familial PD, and strongly influence the risk of sporadic PD. This study investigates the impact of L...
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Identifiers and source
- Literature Corpus work
- 5c32fd8b-3c82-5047-83ae-c35f8a221b6a
- DOI
- 10.21954/ou.ro.000125c8