Article

Aging reveals divergent responses of AgRP/NPY neurons to diet in male and female mice

2025-11-21

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Neurons coexpressing Agouti-related peptide (AgRP) and Neuropeptide Y (NPY) are an essential component of an interoceptive circuit regulating hunger and metabolism. Their activity is closely linked to metabolic state and their output is sensitive to diet-induced plasticity, which may influence the development of obesity and associated metabolic diseases. However, most studie...

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Literature Corpus work: 5bc72cd4-b78b-5827-bfd5-8ab5745ccb7d
DOI: 10.1101/2025.11.20.689576

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