Article
A Small Potassium Current in AgRP/NPY Neurons Regulates Feeding Behavior and Energy Metabolism.
Cell reports - 8 Nov 2016
He Yanlin, Shu Gang, Yang Yongjie, Xu Pingwen, Xia Yan, Wang Chunmei, Saito Kenji, Hinton Antentor, Yan Xiaofeng, Liu Chen, Wu Qi, Tong Qingchun, Xu Yong
Abstract excerpt
Neurons that co-express agouti-related peptide (AgRP) and neuropeptide Y (NPY) are indispensable for normal feeding behavior. Firing activities of AgRP/NPY neurons are dynamically regulated by energy status and coordinate appropriate feeding behavior to meet nutritional demands. However, intrinsic mechanisms that regulate AgRP/NPY neural activities during the fed-to-fasted transition are not fully understood. We...
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