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Article

Altered Metabolic Phenotypes and Hypothalamic Neuronal Activity Triggered by Sodium-Glucose Cotransporter 2 Inhibition.

Diabetes & metabolism journal - 1 Nov 2023

Lee Ho Gyun, Jung Il Hyeon, Park Byong Seo, Yang Hye Rim, Kim Kwang Kon, Tu Thai Hien, Yeh Jung-Yong, Lee Sewon, Yang Sunggu, Lee Byung Ju, Kim Jae Geun, Nam-Goong Il Seong

Abstract excerpt

BACKGRUOUND: Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are currently used to treat patients with diabetes. Previous studies have demonstrated that treatment with SGLT-2 inhibitors is accompanied by altered metabolic phenotypes. However, it has not been investigated whether the hypothalamic circuit participates in the development of the compensatory metabolic phenotypes triggered by the treatment with...

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Identifiers

PMID: 37915185
DOI: 10.4093/dmj.2022.0261
PMCID: PMC10695712

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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