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Article

Cell type-specific transcriptomics of hypothalamic energy-sensing neuron responses to weight-loss

2 Sept 2015

Abstract excerpt

Molecular and cellular processes in neurons are critical for sensing and responding to energy deficit states, such as during weight-loss. Agouti related protein (AGRP)-expressing neurons are a key hypothalamic population that is activated during energy deficit and increases appetite and weight-gain. Cell type-specific transcriptomics can be used to identify pathways that counteract weight-loss, and here we report...

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PMID: 26329458
DOI: 10.7554/elife.09800

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