Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Age-dependent hypothalamic expression of neuropeptides in wild-type and melanocortin-4 receptor-deficient mice.

Physiological genomics - 16 Dec 2003

Arens Janine, Moar Kim M, Eiden Sandra, Weide Karin, Schmidt Ingrid, Mercer Julian G, Simon Eckhart, Korf Horst-W

Abstract excerpt

In young (35- to 56-day-old) and middle-aged (9-mo-old) wild-type (+/+) and melanocortin-4 receptor (MC4R)-deficient (+/-, -/-) mice, expressions of neuropeptide Y (NPY), agouti-related protein (AGRP), pro-opiomelanocortin (POMC), and cocaine-and-amphetamine-regulated transcript (CART) were analyzed in the arcuate nucleus (ARC) and adjacent regions comprising the dorsomedial (DMN) and ventromedial (VMN) nucleus....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Agouti-Related Protein
Share to Hypothalamus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leptin

Share to Models, Animal

Share to Neuropeptide Y

Share to Neuropeptides

Share to Pro-Opiomelanocortin

Share to Receptor, Melanocortin, Type 4

Source

Identifiers

PMID: 14559977
DOI: 10.1152/physiolgenomics.00123.2003

Genes

NPY
AGRP
POMC
ARC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Age-dependent hypothalamic expression of neuropeptides in wild-type and melanocortin-4 receptor-deficient mice.PMID 14559977Read ↗

Agouti-related protein-deficient mice display an age-related lean phenotype.Semantic proximity Read ↗

Aging reveals divergent responses of AgRP/NPY neurons to diet in male and female miceSemantic proximity Read ↗

Hyperphagia, not hypometabolism, causes early onset obesity in melanocortin-4 receptor knockout mice.Semantic proximity Read ↗

Developmental programming of hypothalamic melanocortin circuitsSemantic proximity Read ↗

Induction of neuropeptide Y gene expression in the dorsal medial hypothalamic nucleus in two models of the agouti obesity syndrome.Semantic proximity Read ↗

Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice.Semantic proximity Read ↗

Post-embryonic ablation of AgRP neurons in mice leads to a lean, hypophagic phenotype.Semantic proximity Read ↗

The neuroendocrine circuitry controlled by POMC, MSH, and AGRP.Semantic proximity Read ↗

Effects of hypothalamic neurodegeneration on energy balance.Semantic proximity Read ↗

Expression of ankyrin repeat and suppressor of cytokine signaling box protein 4 (Asb-4) in proopiomelanocortin neurons of the arcuate nucleus of mice produces a hyperphagic, lean phenotype.Semantic proximity Read ↗

Neuropeptides and obesity.Semantic proximity Read ↗

Physiological and anatomical circuitry between Agouti-related protein and leptin signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.